NIA INTERVENTIONS TESTING PROGRAM × CLINICALTRIALS.GOV

THE RACE TO SLOW AGING

Live Scoreboard — ITP Mouse Data × Human Clinical Trials

Tracking every compound tested by the NIA Interventions Testing Program for lifespan extension in mice, plus peer-reviewed longevity compounds validated in published studies — cross-referenced with human clinical trial status from ClinicalTrials.gov.

LAST UPDATED: FEBRUARY 2026
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Compounds Tracked
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ITP Tested
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Peer-Reviewed New
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FDA Approved
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In Human Trials
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Best Δ% (OSK)
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Peak Enrollment
# Compound Category ITP Result Best ♂ Δ% Best ♀ Δ% Human Phase Active Trials Score

What is the ITP?

The NIA Interventions Testing Program is the gold standard for aging research. Each compound is tested at 3 independent sites (Jackson Lab, U-Michigan, UT Health San Antonio) with genetically heterogeneous mice, making results uniquely robust and reproducible.

Composite Score

Calculated from three weighted factors:

  • 40% Best lifespan extension (mouse data)
  • 40% Human trial phase advancement
  • 20% Number of active human trials

ITP Result Icons

✓ Extended both sexes
♂ Males only
✗ No effect
⚠ Harmful
🔬 In progress / not tested

Trial Phase Colors

FDA Approved Phase 3 Phase 2 Phase 1 Preclinical None

Data Visualization

Top 10 Compounds — Lifespan Extension %

Translational Pipeline — Mouse Effect vs. Human Trials

X = Best mouse lifespan Δ% · Y = Human trial phase · Bubble size = Active trials